Best Disease

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Best Disease

What Is Best Disease?

Best disease is an eye condition that affects the central part of the retina at the back of your eye, which is called the macula​. Best disease can start to cause changes at the back of the eye between the ages of 3-15 although it does not usually affect vision until later on in life.

Best disease causes problems with your central vision, but does not lead to total loss of sight and is not painful. Best affects the vision you use when you’re looking directly at something, for example when you’re reading, looking at photos or watching television. Best may make this central vision distorted or blurry and, over a period of time, it may cause a blank patch in the centre of your vision. Best will not usually affect your peripheral (side) vision.

What Are the Causes of Best Disease?

Best Disease is a genetic condition. This means that it is caused by a gene inherited from a parent or occurs as a new genetic variation. It may be inherited as an autosomal dominant trait. Recently the gene responsible for Best disease has been found, but as yet this has not led to any treatment. It has shown, however, that people who have the same fault in this gene can have very different symptoms at different ages, even within the same family.

Is There a Treatment for Best Disease?

Unfortunately, there is no treatment for this eye condition at the moment. Although many advances are being made in identifying genes responsible for Best disease, this hasn’t yet led to a treatment.